# NAD+ and cognition

1 paper in the library, strongest Moderate.

**Graded Moderate**: Double-blind randomized pilot in 42 older adults with amnestic MCI over 12 weeks, though the small sample and short duration leave the findings unsettled.

## Papers (1)

- [NAD+ Booster Raised Cellular Fuel But Didn't Improve Memory in 12 Weeks](https://usa-longevity.com/en/research/nad-booster-raised-cellular-fuel-but-didn-t-improve-memory-in-12-weeks) · Moderate · n = 42 · 2026 · Alzheimer's & dementia : the journal of the Alzheimer's Association

## How this map is computed

A mark's size is the number of papers we hold on that pairing. It is a count, not a weighting by study design or sample size.

The fill shows the strongest grade in the cell. One Strong paper among four Preliminary ones still fills it dark, so open the cell to see the rest.

Grades and verdicts are assigned by a named person, never by counting.

An empty cell is a finding: nobody in our library has run that trial yet.

---

_Canonical: https://usa-longevity.com/en/evidence/nad-precursors/cognition · Part of Longevity Cities_