# Some Supplements May Nudge Memory Scores in People With Alzheimer's

*The impact of supplements on cognitive function for Alzheimer's disease or mild cognitive impairment: a systematic review and network meta-analysis.*

- **Evidence Level**: Moderate
- **Publication Types**: Journal Article, Review
- **Journal**: Nutritional neuroscience
- **Sample Size**: 2,000 adults with Alzheimer's or mild cognitive impairment (29 trials)
- **Authors**: Li Y, Leng Q, Wang Y
- **Published**: 2026-07-23
- **Topics**: cognition, supplements, Alzheimer's
- **DOI**: https://doi.org/10.1080/1028415X.2026.2703619
- **Original Source**: https://pubmed.ncbi.nlm.nih.gov/42494057/

## Summary

Researchers pooled dozens of trials to see which supplements help thinking in people with Alzheimer's or mild memory loss. A few, like phosphatidylserine, spirulina, B vitamins, and a probiotic-selenium combo, showed small improvements on one memory test. But none helped on a second, more detailed test. So the wins are modest and depend heavily on how you measure them.

## Practical Takeaway

This review suggests certain supplements may offer small memory benefits in people with cognitive decline.

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