What is the Longevity Research Library?

The Longevity USA Research Library curates recent peer-reviewed studies on longevity, nutrition, exercise, sleep, and supplements. Each study is rated by evidence strength: Strong, Moderate, or Preliminary.

How are evidence levels determined?

Evidence levels are based on study type (meta-analysis, RCT, cohort study), sample size, journal impact factor, and reproducibility of findings.

77 studies

Research Library

Peer-reviewed papers from top journals, summarized and graded by evidence strength. Updated Mon, Wed & Fri.

5/77

Apr 5–11, 2026

Eating More Fruits, Fish, Nuts, and Dairy Tied to Slower Cognitive Decline

In over 3,000 Chinese older adults tracked for about five years, those who ate more from six protective food groups (fruits, vegetables, nuts, legumes, fish, and dairy) showed slower cognitive decline. People scoring highest on this diet scale declined about 0.42 points per year slower on a cognitive test compared to those scoring lowest. The effect was modest but consistent across different ways of measuring cognition.

NPJ science of food·Moderate·Apr 9, 2026

Mar 29 – Apr 4, 2026

Longevity Protein Klotho May Protect Against Cognitive Decline in Parkinson's

People with Parkinson's disease who carry a specific variant of the klotho gene tended to perform better on executive thinking tasks across two separate groups. In mice engineered to model Parkinson's, boosting klotho levels improved brain function and reduced alpha-synuclein (a toxic protein that builds up in Parkinson's). The cognitive benefits showed up without improving motor symptoms. Lab experiments suggested klotho may work by helping brain cells clear that toxic protein more effectively.

The Journal of neuroscience : the official journal of the Society for Neuroscience·Preliminary·Mar 31, 2026

Why Even One Workout Sharpens Your Thinking, According to Research

A single session of moderate to vigorous exercise reliably boosts executive function, processing speed, and working memory in adults. Cardio led the pack, but resistance training also improved executive function in many trials. The brain benefits seem tied to short-term spikes in BDNF, lactate, and prefrontal brain activity. So even one workout appears to give your brain a temporary lift.

Muscles (Basel, Switzerland)·Moderate·Mar 30, 2026

Mar 15–21, 2026

Two Opposing Brain Fuel Patterns May Predict Who Keeps Their Cognition With Age

Brain white matter (the wiring that connects brain regions) uses glucose differently depending on where you look. In over 3,000 participants across two studies, higher glucose use in expected areas like the corpus callosum linked to better thinking skills. But higher glucose use in unusual areas like the corona radiata linked to worse cognition, likely a sign the brain is compensating. Over time, people with strong "normal" metabolism and low "compensatory" metabolism declined more slowly.

Nature communications·Moderate·Mar 19, 2026

Worse Metabolic Syndrome Tied to Faster Cognitive Decline in Older Adults

Among Chinese adults over 60, having more severe metabolic syndrome was linked to faster mental decline over several years. The connection held for both overall cognition and memory specifically. People in the worst quarter of cumulative metabolic syndrome scores declined in memory about three times faster than those in the best quarter. These findings come from two large studies tracking participants for up to eight years.

Frontiers in neuroscience·Moderate·Mar 17, 2026

Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.

Your Weekly Edge

Receive the latest longevity insights, exclusive event invites, and science-backed tips to help you live longer and thrive.