Fat Tissue Controls Lifespan Through Insulin Signaling in Fruit Flies
In fruit flies, dialing down a gene called Dicer-1 in fat tissue extended lifespan. It worked even when flies were already on calorie restriction. The mechanism involves a chain reaction: lower Dicer-1 reduces a small RNA molecule in fat, which boosts a hormone that then tells the brain to release less insulin. Less insulin signaling is a well-known longevity pathway across species.
Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.
Related Studies
All researchJust 5,700 Daily Steps Cut Death Risk By 13% In Older Adults
Looking at dozens of studies with over 367,000 older adults, regular walking was tied to lower risk of death, disease, and cognitive…
Quail Bred to Reproduce More Aged Faster, Supporting a Core Theory of Aging
Researchers selectively bred Japanese quail for higher or lower reproductive effort across several generations.
We May Not Be Aging Slower. We're Just Starting Later.
A big question in longevity research is whether rising life expectancy means we're actually aging more slowly.