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Journal ArticlePreprintResearch square·Jun 2026

Nicotinamide Riboside Improved Movement in Parkinson's Mice Without Saving Neurons

Key Insight

This mouse study suggests NR may ease Parkinson's movement problems by boosting cell energy.


Nicotinamide riboside (NR), a popular NAD-boosting supplement, improved movement in mice with a Parkinson's-like condition. It did this by boosting energy production in cells and increasing dopamine signaling, even though it did not stop brain cells from dying. So the benefit came from making the surviving cells work better, not from protecting them. This was in mice, so it's a hint at a possible add-on strategy, not proof for people.

Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.