Common Bone Drugs May Also Slow Aging in the Heart and Liver
Graded Moderate — plasma proteomics from postmenopausal women in a randomized trial, though the human evidence is limited to protein changes and the rest comes from aged mice and human cells.
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- NIA NIH HHS; Foundation for the National Institutes of Health (Foundation for…
This study suggests bone drugs may have wider anti-aging effects, but that needs dedicated human trials.
Bisphosphonates are old, widely used drugs for bone loss like osteoporosis. This study found they may do far more than protect bones. In aged mice and in blood from women in a trial, these drugs shifted aging markers toward a younger pattern in the heart, liver, and gut. They also protected human heart cells from becoming worn out and damaged.
Conflict of Interest Disclosure: The authors declare no competing interests.
Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.