Metformin Added Nothing to Diet and Exercise for Older Adults' Strength
This study suggests structured exercise and diet drive physical function gains, not metformin.
Metformin has a big fan club in longevity circles, but this trial puts a dent in the hype. Older adults with obesity, aged 65 to 85, did six months of serious diet and exercise coaching. Adding metformin on top gave zero extra improvement in physical function compared to a placebo. The lifestyle program itself was what moved the needle.
Conflict of Interest Disclosure: None declared; funded by the US Department of Veterans Affairs.
Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.
Related Studies
All researchA 9-Year Mailed Exercise Program Barely Moved the Needle in Older Women
Nearly 50,000 women aged 66 to 99 were randomly assigned to a long-running, remotely delivered program that encouraged more movement and…
Why Small Nutrient Gaps May Quietly Speed Up Aging After Your 40s
This review argues that common shortfalls in vitamins and minerals like B vitamins, C, D, E, zinc, and selenium may speed up biological…
How Exercise Quiets a Muscle-Wasting Inflammation Signal in Older Women
Scientists found a specific inflammation signal called CXCL2 that climbs as muscle loss gets worse with age.
