CRON (Caloric Restriction with Optimal Nutrition)

CRON is a structured form of caloric restriction in which energy intake is reduced by roughly 20–30% while micronutrient density (vitamins, minerals, essential fatty acids, protein quality) is deliberately maximized. The approach was developed by Roy Walford, Lisa Walford, and Brian M. Delaney, with The Anti-Aging Plan (1994) as a key reference, and later promoted by the CR Society. The aim is to capture metabolic benefits—improved insulin sensitivity, lower inflammation, favorable lipids—without inducing nutrient deficiencies.