NMN Plus Apigenin May Protect Aging Muscle and Bone Better Together
This study suggests combining NAD boosters with apigenin may better preserve musculoskeletal health in aging.
In aged mice, combining the NAD booster NMN with apigenin (a compound found in parsley and chamomile) reduced cartilage breakdown, bone loss, and muscle wasting. The combo works by both producing more NAD+ and blocking enzymes that consume it. Treated mice also showed better exercise capacity. The benefits appeared to work through SIRT3 activation and changes in gut bacteria that produce a helpful fat molecule.
Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.
Topics
Related Studies
All researchA Common Flame Retardant Made Alcohol Damage Worse, and NAD+ Reversed It
Zebrafish exposed to DBDPE, a flame retardant found in furniture and electronics, handled an alcohol hit much worse than usual.
Why Low NAD+ May Push Insulin-Making Cells Into Self-Inflicted Inflammation
In cells and animals, oxidative stress drained NAD+ inside the insulin-producing cells of the pancreas, flipping a chemical switch that set…
Exercise Helps Aging Brains Most If You're Older or Mostly Sedentary
Middle-aged and older adults who moved more had healthier-looking brain wiring on MRI scans, but the benefit wasn't the same for everyone.