Zum Inhalt springen
The Journal of neuroscience : the official journal of the Society for Neuroscience·März 2026

Longevity Protein Klotho May Protect Against Cognitive Decline in Parkinson's

Kernaussage

This study suggests klotho-related therapies could one day target cognitive decline in Parkinson's.


People with Parkinson's disease who carry a specific variant of the klotho gene tended to perform better on executive thinking tasks across two separate groups. In mice engineered to model Parkinson's, boosting klotho levels improved brain function and reduced alpha-synuclein (a toxic protein that builds up in Parkinson's). The cognitive benefits showed up without improving motor symptoms. Lab experiments suggested klotho may work by helping brain cells clear that toxic protein more effectively.

Haftungsausschluss: Forschungszusammenfassungen dienen nur zu Informationszwecken und stellen keine medizinische Beratung dar. Konsultiere immer einen qualifizierten Arzt, bevor du Änderungen an deiner Gesundheitsroutine vornimmst.