What is the Longevity Research Library?

The Longevity USA Research Library curates recent peer-reviewed studies on longevity, nutrition, exercise, sleep, and supplements. Each study is rated by evidence strength: Strong, Moderate, or Preliminary.

How are evidence levels determined?

Evidence levels are based on study type (meta-analysis, RCT, cohort study), sample size, journal impact factor, and reproducibility of findings.

59 studies

Research Library

Peer-reviewed papers from top journals, summarized and graded by evidence strength. Updated Mon, Wed & Fri.

4/59

This week

Three Ways to Measure Biological Age All Predict Heart Disease

In over 320,000 UK adults followed for nearly 14 years, accelerated biological aging predicted heart trouble across the board. Depending on which aging clock was used, faster aging raised heart failure risk by 26% to 52% per standard deviation. Adding these biological age scores to standard risk models improved prediction of who would develop heart disease.

Heart & lung : the journal of critical care·Strong·Apr 28, 2026

When Your Body Ages Faster Than Your Birthday, Your Heart Pays the Price

In over 31,000 UK adults, those whose biological age outpaced their actual age had clearly worse heart outcomes. Each extra 4.6 years of biological aging meant a 29% higher risk of heart failure and a 16% higher risk of dying from heart disease. Heart scans showed these people also had weaker, smaller heart muscles. Women seemed more affected than men.

The journals of gerontology. Series A, Biological sciences and medical sciences·Strong·Apr 27, 2026

Mar 29 – Apr 4, 2026

Your Brain May Slow Down Years Before a Heart Attack or Stroke

In older adults, thinking skills started declining 3 to 8 years before they had a major cardiovascular event like a stroke or heart failure. The drops showed up in memory, processing speed, and verbal fluency compared to people who stayed healthy. This hints that heart disease and brain aging share deep roots, and subtle cognitive changes might be an early warning sign.

JAMA network open·Moderate·Mar 31, 2026

Mar 8–14, 2026

How Mutant Blood Stem Cells May Quietly Fuel Heart Disease as You Age

As people age, blood stem cells accumulate mutations that cause certain cell lines to expand. This process, called clonal hematopoiesis, is now strongly linked to increased cardiovascular risk in older adults. The mutant blood cells appear to ramp up inflammation, accelerating atherosclerosis and heart failure. This review covers how these rogue clones interact with age-related inflammation and what future therapies might look like.

Acta pharmacologica Sinica·Moderate·Mar 15, 2026

Disclaimer: Research summaries are provided for informational purposes only and do not constitute medical advice. Always consult a qualified healthcare professional before making changes to your health routine.

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